BDBM50438865 2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-carbonitrile (3)::CHEMBL2420506

SMILES O=c1nc2n(-c3ccccc3)c3cc(ccc3cc2c(=O)[nH]1)C#N

InChI Key InChIKey=KJCUSTLTHCEPIZ-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438865   

TargetTyrosyl-DNA phosphodiesterase 2 [E242G,S244A,Q278R,I281T,K282R,R316G,P318T,Y321C](Mus musculus (Mouse))
National Institutes of Health

LigandPNGBDBM50438865(2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-car...)
Affinity DataIC50:  3.70E+3nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed